2. San Francisco-San Mateo-Redwood City (Calif.)
Metro population: 1.7 million
Unemployment rate: 7 percent
Cost of living index: 193 (100 is average)
San Francisco is the No. 1 city for indie culture and there are a ton of young people. Plus, it’s a very dense city with a great transportation system, which makes it easier to get around. Plus, it’s a very green city, situated on the San Francisco Bay and close to a lot of outdoor actives, Sperling’s Best Places says.