In 1893 America, New York is part of the Free States, where people may live and love whomever they please. The fragile young scion of a distinguished family resists betrothal to a worthy suitor, drawn to a charming music teacher of no means. In a 1993 Manhattan surrounded by the AIDS epidemic, a young Hawaiian man lives with his much older, wealthier partner, hiding his troubled childhood and the fate of his father. In 2093, in a world riven by plagues and governed by totalitarian rule, a powerful scientist’s damaged granddaughter tries to navigate life without him — and solve the mystery of her husband’s disappearances. What unites not just the characters, but these Americas, are their reckonings with the qualities that make us human: Fear. Love. Shame. Need. Loneliness.