Regardless of whether you are cooking the entire meal or just one dish, consider substituting healthier ingredients when possible. For instance, use Greek yogurt in place of sour cream or mayonnaise. And, fat-free half-and-half won’t be noticed if substituted for its fatter cousin. Deglaze pans with low-sodium vegetable stocks. But, be very careful about any margarine selection. Many have so many chemicals that any savings on calories or fat is negligible. Try I Can’t Believe It’s Not Butter! or Benecal brands. But, your grandmother and Paula Deen are on to something: nothing beats real, pure butter. All natural, the body knows exactly what to do with it.