You have a plethora of options in the nightclub category: Pretty much every casino on the strip and downtown have one, but these are pretty much the best and most popuar: The LAX at the Luxor; The Bank at the Bellagio; The Club Surrender; Tao at the ultra-upscale Venetian, Club Tabu at the MGM, Pure at Caesars, The Cathouse at the Luxor or, one of my personal favorites, Eyecandy at the Mandalay Bay.