7. Refuse to give in. No matter how discouraged, frustrated, or desperate you might feel, finding the resolve to never give in will help keep depression from putting more nails in your coffin. If you are blessed enough to have identified your purpose or passion in life, keep that thing at the forefront of all you do. When you feel like you are living with purpose, be it for yourself or for others, you’ll create a reason to make it past the doom and gloom. Trust me. I’ve been there. But I found my passion, and I’m still here.